GENETIC ENGINEERING - Gene Synthesis

Biomedal Gene Synthesis Service is designed for synthesizing genes de novo, from the sequence of the target gene. For oligo synthesis, it is a single strand, and the longest oligo people can synthesize is only about 140 bases, for Gen Synthesis, it is double-strand, the genes can be anything from 3.000 bp.

Application Examples:

• - Codon optimization to boost protein expression.
• - Replace PCR products cloning.
• - Large-scale production of cDNA fragments for microarray chip.
• - Clone humanised mouse antibodies or recombinant antibodies.
• - Synthesis cDNAs for which the corresponding mRNA sources are difficult to obtain.
• - Synthesis predicted genes/cDNAs.
• - Synthesis genes or cDNAs that are difficult to clone.
• - Synthesis alternative spliced gene variants, SNPs, or any other variant type.
• - Design gene therapy vector or genes.
• - Design DNA vaccines.
• - Design your own genes/cDNAs (deletion, mutation, and rearrangement, etc.).
• - Modify your gene for structure-function studies.

GENE SIZE	LEAD TIME (WORKING DAYS)
0-1.000 pb	17 days
1.000-3.000 pb	22 days
>3.000 pb	Inquired

The synthesized gene is cloned in a vector, either provided by the client or chosen between the different vectors of Biomedal´s catalogue, and its sequence confirmed before the delivery. Accompanying the synthesized gene we give a map of inserted gene, a plasmic map that contain the inserted gene, documentation about the clone squences, quality certificate, and approximately 4 µg of lyophilized plasmic with the gene desired.

Ref.	Product
SE-3348	Gene Synthesis and Cloning